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Sorbent Management for Advanced Renal Replacement Therapy (SMARRT™)
Sorbent dialysis is different from other hemodialysis therapies. Sorbent dialysis is a unique, on-line regenerative type of dialysis. It is the sorbent cartridge that makes this system simple. Spent dialysate from the dialyzer flows through the sorbent cartridge where the waste metabolites are removed. The regenerated dialysate leaving the cartridge consists of sodium chloride, sodium bicarbonate, sodium acetate, carbon dioxide, and water. An infusate system adds calcium, magnesium, and potassium resulting in a fully regenerated dialysate for recirculation to the dialyzer.
Only a small amount of dialysate made from approximately 1½ gallons (6 liters) of potable tap water is necessary to perform a 3-8 hour dialysis procedure; therefore, water is conserved. Potable tap water can be used because the sorbent cartridge is also the water treatment system. This not only eliminates the need to purchase and maintain an expensive water treatment system, but provides an unusual degree of transportability compared to conventional dialysis systems. The dialysis provider is also freed of high utility bills to pump and heat large volumes of dialysate and the expense of water treatment equipment and special sodium and bicarbonate proportioning systems. There are no water supply or drain hoses to leak or to create a hazard.
Sorbent systems have a closed dialysate pathway. During a treatment, nothing, not even ultrafiltrate, goes down a drain. Thus, any increase in the volume of dialysate in the system is due to the accumulation of ultrafiltrate. Therefore, a direct measurement of ultrafiltration is provided, not an estimate.
Because sorbent systems do not require special wiring or plumbing, sorbent dialysis can be performed almost anywhere: in dialysis centers, critical care units, hospital rooms, emergency rooms, nursing homes, disaster response, and self-care environments.
Sorbent dialysis is a simpler hemodialysis therapy option when compared with far more complex single-pass dialysis. This unique sorbent dialysis therapy brings new levels of convenience, safety and flexibility to hemodialysis. Now, that’s SMARRT.
Only 6L of potable tap water!
Download the PDF to learn about the history of sorbent dialysis.
It is not necessary to connect the sorbent system to a drain or to continuously provide water and concentrate to the system during dialysis. As a result, there are no water supply or drain hoses to leak or to create a hazard.